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What Are The New COVID Variants NB.1.8.1 And LF.7 That Are Sparking Fresh Concerns In India?

India has detected two new COVID-19 variants, NB.1.8.1 and LF.7, prompting increased monitoring by health authorities. While overall cases remain low, experts are evaluating the variants’ potential for immune escape and higher transmission. States like Gujarat and Tamil Nadu have reported initial cases, leading to localised alerts.

by Siddhi Tendulkar
What Are The New COVID Variants NB.1.8.1 And LF.7 That Are Sparking Fresh Concerns In India?

India is again witnessing a rise in COVID-19 cases, driven by the detection of two new variants – NB.1.8.1 and LF.7. Although the country currently reports a low number of active cases, health officials are on alert. These variants have drawn attention due to their mutation profiles and potential impact on transmission and immunity. With cases being reported from states like Gujarat and Tamil Nadu, authorities have started monitoring the situation closely.

COVID-19 Variants NB.1.8.1 And LF.7 Are Being Monitored

COVID-19 variants
Picture Credits: Canva Pro

The Indian SARS-CoV-2 Genomics Consortium (INSACOG) has confirmed the presence of the country’s NB.1.8.1 and LF.7 variants. According to a report by India Today, one case of NB.1.8.1 was identified in Tamil Nadu, while four cases of LF.7 were reported in Gujarat. These two lineages have been added to the World Health Organization’s (WHO) list of variants under monitoring.

NB.1.8.1 is a descendant of the Omicron subvariant BA.2.75 and includes specific mutations such as A435S, V445H, and T478I on the spike protein. These mutations may potentially allow the virus to spread more efficiently and evade existing immunity. Similarly, LF.7, a sub-lineage of JN.1, is known to have enhanced immune escape properties.

Also Read: COVID Cases Rise Again In Asia; Surge Reported In China, Thailand, Hong Kong, And Singapore

As reported by The Times of India, health experts are currently evaluating the impact of these mutations. Both variants are still under study and have not been classified as variants of concern. However, increased surveillance is underway.

COVID-19 Situation In India

Despite the emergence of new variants, the total number of active COVID-19 cases in India remains relatively low. According to the Ministry of Health and Family Welfare, India reported 257 active cases as of May 19. The majority of infections continue to be caused by the JN.1 variant, followed by BA.2 and other Omicron-related strains.

Also Read: COVID-19 Cases Rise In Asia; India Logs 257 Mild Infections, Says Health Ministry

A few states, including Delhi, Andhra Pradesh, Telangana, Kerala, and Karnataka, have reported slight increases in case numbers. However, the rise is not consistent across all regions. The current wave does not resemble past surges in terms of hospitalisations or deaths.

Public Response And Preventive Measures

Authorities are urging people to remain cautious while avoiding unnecessary panic. As reported by The Economic Times, health officials recommend wearing masks in crowded places, practising good hand hygiene, and staying updated on vaccinations.

Also Read: India Faces New COVID-19 Surge As Mumbai, Chennai, And Gurgaon Report Rising Cases

While the government considers COVID-19 to have entered an endemic phase in India, tracking emerging variants like NB.1.8.1 and LF.7 remains essential. Surveillance, genome sequencing, and timely updates from state health departments are playing a vital role in controlling localised outbreaks.

Cover Image Courtesy: Canva Pro

First Published: May 26, 2025 12:18 PM